So i avoided reading as much as i could but now i cant help myself
Lockpicking will be just like Fallout 3
Crafting is in
Enchantment, Smithing and Alchemy More like MMO crafting than previous.
I was worried about Skills and levelling as they "streamlined" the process (i translated as console kiddies go wah if its hard), seems its very similar to that in Fallout skill ups (any, no more major/minor skills) add up until you level up. At level up you get a perk to spend, each skill has its own perk tree