I'm playing on a an old laptop with 1 gig of memory and an ati radeon x700 mobility.
I've got everyhting, EVERYTHING turned off.
It runs alright if I avoid RVR, let it load at start until my 'I'm busy' light on my laptop stops going blinky blinky and grant it 2,5 mins to log out or 5 mins to exit to desktop. So I basically alt tab and end process.
No issues with sound. Are your drivers for audio and video entirely up to date?